Research Publications & Papers
Explore scientific articles, open-access genomics datasets, and high-impact multi-omics findings authored by HG-Omics scientists and fellowship teams.
Whole-Genome Landscape and Germline Susceptibility Markers in South Asian Population Cohorts
Authors: Tariqul Islam, Farzana Rahman, S. M. Nazmul Hossain, et al.
ABSTRACT:Comprehensive high-throughput whole-genome sequencing of 1,500 individuals revealed novel population-specific single nucleotide variants (SNVs) associated with metabolic traits and hereditary cancer susceptibility.
Single-Cell RNA-Seq Uncovers Microenvironmental Heterogeneity in Triple-Negative Breast Cancer
Authors: Mahmuda Chowdhury, Tanvir Ahmed Chowdhury, Nusrat Parveen, et al.
ABSTRACT:Characterizing 45,000 single-cell transcriptomic profiles identified tumor-infiltrating lymphocyte subtypes associated with anti-PD1 therapy response rates.
Deep Neural Network Framework for Automated Pathogenic Variant Classification in Non-Coding Genomic Regions
Authors: Tanvir Ahmed Chowdhury, Kazi Minhazur Rahman, Tariqul Islam
ABSTRACT:Developing a 1D Convolutional Attention Network (1D-CAN) capable of predicting enhancer and promoter variant impact with 94.2% ROC-AUC accuracy.
Gut Microbiome Dysbiosis and Metabolic Gene Profiling in Type 2 Diabetes Patients
Authors: Nusrat Parveen, Farzana Rahman, Afsana Jahan, et al.
ABSTRACT:Metagenomic shotgun profiling demonstrated depleted Akkermansia muciniphila abundance correlated with elevated HbA1c levels in urban patient groups.